BDBM50379195 CHEMBL2010869

SMILES CCCn1c2ccc(Nc3ncc(CC)cn3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12

InChI Key InChIKey=NYZJRFCPAIKBKR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50379195   

TargetAngiopoietin-1 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50379195(CHEMBL2010869)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant Tie2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50379195(CHEMBL2010869)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant VEGF-R2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed