BDBM50379145 CHEMBL2012827::US8703811, 35

SMILES O=C(NC1CCCC1)c1ccc(s1)-n1cnc2ccccc12

InChI Key InChIKey=YPLDVMVXDLUZQR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50379145   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. falciparum)
Genzyme

US Patent
LigandPNGBDBM50379145(CHEMBL2012827 | US8703811, 35)
Affinity DataIC50: 2.51E+3nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50379145(CHEMBL2012827 | US8703811, 35)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed