BDBM50378780 (S)-VOROZOLE

SMILES Cn1nnc2ccc(cc12)[C@H](c1ccc(Cl)cc1)n1cncn1

InChI Key InChIKey=XLMPPFTZALNBFS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50378780   

TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50378780((S)-VOROZOLE)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of STS activity (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50378780((S)-VOROZOLE)
Affinity DataIC50: 29nMAssay Description:Inhibition of aromatase (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50378780((S)-VOROZOLE)
Affinity DataIC50: 1.38nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50378780((S)-VOROZOLE)
Affinity DataIC50: 9.50E+4nMAssay Description:In vitro inhibition of ACTH-stimulated corticosterone biosynthesis in rat adrenal slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Rat)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50378780((S)-VOROZOLE)
Affinity DataIC50: 1.20E+4nMAssay Description:In vitro inhibition of ACTH-stimulated aldosterone biosynthesis in rat adrenal slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed