BDBM50377826 CHEMBL402979

SMILES Oc1ccc(cc1)C(=O)CN1CCC(Cc2ccc(cc2)N=C=S)CC1

InChI Key InChIKey=QRRWZRWYDBHGIU-UHFFFAOYSA-N

Data  1 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50377826   

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377826(CHEMBL402979)
Affinity DataEC50: >1.00E+5nMAssay Description:Activity at NR1/NR2A receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current responseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377826(CHEMBL402979)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of NR1/NR2A receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current responseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377826(CHEMBL402979)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of NR1/NR2B receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current responseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377826(CHEMBL402979)
Affinity DataIC50: 5.70E+5nMAssay Description:Inhibition of N-terminal domain truncated NR1/NR2B receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced curren...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377826(CHEMBL402979)
Affinity DataKi:  245nMAssay Description:Displacement of [3H]ifenprodil from rat brain membrane NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed