BDBM50377588 CHEMBL257594

SMILES Cc1ccc2c(NNC(=O)c3ccccc3O)c3ccccc3nc2c1C

InChI Key InChIKey=ZJTYPGUYLZBCCX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50377588   

TargetCathepsin D(Human)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50377588(CHEMBL257594)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human cathepsin D by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50377588(CHEMBL257594)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50377588(CHEMBL257594)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant Plasmodium falciparum Plasmepsin 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCathepsin D(Human)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50377588(CHEMBL257594)
Affinity DataIC50: 9nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed