BDBM50376902 CHEMBL408194

SMILES COC1=CC(=N\C1=C/c1[nH]c(C)cc1C)c1cc2ccccc2[nH]1

InChI Key InChIKey=RFTSSZJZXOSICM-UHFFFAOYSA-N

Data  10 KI  3 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50376902   

TargetBcl-2-related protein A1(Human)
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)
Affinity DataEC50:  600nMAssay Description:Inhibition of GST-tagged recombinant Bfl1 interaction with biotinylated Bim peptide by ELISA based competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)
Affinity DataEC50:  500nMAssay Description:Inhibition of GST-tagged recombinant Mcl1 interaction with biotinylated Bim peptide by ELISA based competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)
Affinity DataEC50:  300nMAssay Description:Inhibition of GST-tagged recombinant Bcl2 interaction with biotinylated Bim peptide by ELISA based competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of Mcl-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2020
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Hunan Provinc

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)
Affinity DataIC50: 4.69E+3nMAssay Description:Inhibition of Bcl-xL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2020
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2020
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Hunan Provinc

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)
Affinity DataEC50:  900nMAssay Description:Inhibition of GST-tagged recombinant Bcl-XL interaction with biotinylated Bim peptide by ELISA based competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBcl-2-like protein 10 [11-204](Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of BH3 peptide binding to human recombinant BCL-b by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetBcl-2-related protein A1(Human)
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of BH3 peptide binding to human recombinant A1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of BH3 peptide binding to human recombinant BCL-w by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of BH3 peptide binding to human recombinant MCL1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of BH3 peptide binding to human recombinant BCL-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)
Affinity DataKi:  1.11E+3nMAssay Description:Inhibition of Bcl2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of MCl-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Hunan Provinc

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)
Affinity DataKi:  4.69E+3nMAssay Description:Inhibition of Bcl-xL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of adenosine receptor A1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)
Affinity DataKi:  7.01E+3nMAssay Description:Inhibition of Bcl-w (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed