BDBM50374770 CHEMBL407035

SMILES CS(=O)(=O)c1ccc(\C=C(\C(O)=O)c2ccc(F)cc2)cc1

InChI Key InChIKey=PERMQNUWKOEGBE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50374770   

TargetAldo-keto reductase family 1 member C2(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50374770(CHEMBL407035)
Affinity DataIC50: 4.46E+4nMAssay Description:Inhibition of recombinant AKR1C2 (unknown origin) assessed as decrease in oxidation of 1-acenaphthenol substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C1(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50374770(CHEMBL407035)
Affinity DataIC50: 2.33E+4nMAssay Description:Inhibition of human recombinant AKR1C1 expressed in Escherichia coli assessed as decrease in oxidation of 1-acenaphthenol substrate by spectrophotome...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50374770(CHEMBL407035)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of ovine COX2 by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50374770(CHEMBL407035)
Affinity DataIC50: 400nMAssay Description:Inhibition of ovine COX1 by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50374770(CHEMBL407035)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article