BDBM50374666 CHEMBL259450

SMILES CCc1ccccc1NC(=O)CSC(=O)NNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C

InChI Key InChIKey=OTIWAYTTYNFEKL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50374666   

TargetProcathepsin L(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50374666(CHEMBL259450)
Affinity DataIC50: 56nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50374666(CHEMBL259450)
Affinity DataIC50: 56nMAssay Description:Inhibition of cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50374666(CHEMBL259450)
Affinity DataIC50: 56nMAssay Description:Inhibition of human recombinant Cathepsin L assessed as Kinact using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProcathepsin L(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50374666(CHEMBL259450)
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of human liver Cathepsin L using Z-Phe-Arg-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed