BDBM50373010 CHEMBL272548

SMILES COc1cnn(C)c(=O)c1-c1ccc(C[C@H](NC(=O)c2c(Cl)cccc2Cl)c2nnn[nH]2)cc1

InChI Key InChIKey=FOUDHXTZQKEKBC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50373010   

TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50373010(CHEMBL272548)
Affinity DataIC50: 89nMAssay Description:Inhibition of human integrin alpha-4-beta-7-mediated K562 cell adhesion to immobilized MAdCAM1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50373010(CHEMBL272548)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human integrin alpha-4-beta-1-mediated Ramos cell adhesion to immobilized VCAM1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed