BDBM50372113 CHEMBL429734

SMILES Cc1oc(nc1CCOc1cccc(C[C@H]2[C@H](N(C2=O)c2ccc(cc2)C(C)(C)C)C(O)=O)c1)-c1cccc(Cl)c1

InChI Key InChIKey=RFKDHOWUSOAINF-UHFFFAOYSA-N

Data  6 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50372113   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50372113(CHEMBL429734)
Affinity DataEC50:  100nMAssay Description:Agonist activity at PPARgamma in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50372113(CHEMBL429734)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human ERG by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50372113(CHEMBL429734)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50372113(CHEMBL429734)
Affinity DataIC50: 860nMAssay Description:Inhibition of PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50372113(CHEMBL429734)
Affinity DataEC50:  60nMAssay Description:Agonist activity at PPARalpha in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50372113(CHEMBL429734)
Affinity DataIC50: 670nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50372113(CHEMBL429734)
Affinity DataIC50: 250nMAssay Description:Inhibition of PPARgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50372113(CHEMBL429734)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 in presence of 7-benzyloxyresorufin substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed