BDBM50371970 CHEMBL89506

SMILES CCCCCCCCSCC(=O)C(F)(F)F

InChI Key InChIKey=WMQHRXUKAYSPPK-UHFFFAOYSA-N

Data  2 KI  36 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 38 hits for monomerid = 50371970   

Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant iPLA2 assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 63nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPE as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPE as substrate assessed as assessed as reduction in free AA formation after 30 mins...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 83nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PLPC as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 67nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PLPC as substrate assessed as reduction in free AA formation after 30 mins by HPLC-MS ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPA as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPG as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 49nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free AA formation after 30 mins by HPLC-MS ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPA as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 63nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPE as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 49nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free AA formation after 30 mins by HPLC-MS ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant iPLA2 assessed as reduction in free FA formation after 30 mins by HPLC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free [14C]-AA formation after 30 mins by sc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPG as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 54nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 46nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPS as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPE as substrate assessed as assessed as reduction in free AA formation after 30 mins...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 67nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PLPC as substrate assessed as reduction in free AA formation after 30 mins by HPLC-MS ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 54nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant iPLA2 assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLiver carboxylesterase(Pig)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of pig liver carboxylesterase after 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarboxylic ester hydrolase(Tobacco hawkmoth)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 22nMAssay Description:Inhibition of Manduca sexta juvenile hormone esteraseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetLiver carboxylesterase 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant carboxylesterase 1 after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLiver carboxylesterase 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant carboxylesterase 1 after 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human recombinant carboxylesterase 2 after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human recombinant carboxylesterase 2 after 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant FAAH after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant FAAH after 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetJuvenile hormone esterase, isoform B(Cabbage looper)
University of California At Davis

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Trichoplusia ni (cabbage looper) juvenile hormone esterase isolated from fifth-intsar larval stage using [3H]JH 3 as substrate incubate...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLiver carboxylesterase(Pig)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 37nMAssay Description:Inhibition of Sus scrofa (pig) carboxylesterase isolated from liver in using p-nitrophenyl acetate as substrate incubated for 5 min prior to substrat...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLiver carboxylesterase B-1(Rat)
University of California At Davis

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 37nMAssay Description:Inhibition of carboxylesterase in Fischer 344 Rattus norvegicus (rat) liver microsomes using p-nitrophenyl acetate as substrate incubated for 5 min p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant iPLA2 assessed as reduction in free FA formation after 30 mins by HPLC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free [14C]-AA formation after 30 mins by sc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 46nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPS as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 83nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PLPC as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLiver carboxylesterase(Pig)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of pig liver carboxylesterase after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLiver carboxylesterase 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataKi:  4.17nMAssay Description:Inhibition of human carboxylesterase 1 after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLiver carboxylesterase 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataKi:  191nMAssay Description:Inhibition of human carboxylesterase 1 after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed