BDBM50369390 CHEMBL54224

SMILES c1nc2c(n1[C@H]3CC[C@H](O3)CO[P@@](=O)(O)O[P@](=O)(O)OP(=O)(O)O)N=C(NC2=O)N

InChI Key InChIKey=HDRRAMINWIWTNU-UHFFFAOYSA-N

Data  7 IC50

PDB links: 22 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50369390   

TargetTelomerase reverse transcriptase(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50369390(CHEMBL54224)
Affinity DataIC50: 8.60E+3nMAssay Description:Concentration required to inhibit telomerase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Universidad De Alcal£

Curated by ChEMBL
LigandPNGBDBM50369390(CHEMBL54224)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibitory activity against R172A mutant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Universidad De Alcal£

Curated by ChEMBL
LigandPNGBDBM50369390(CHEMBL54224)
Affinity DataIC50: 855nMAssay Description:Inhibitory activity against wild-type HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Universidad De Alcal£

Curated by ChEMBL
LigandPNGBDBM50369390(CHEMBL54224)
Affinity DataIC50: 875nMAssay Description:Inhibitory activity against E138K mutant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Rutgers University

Curated by ChEMBL
LigandPNGBDBM50369390(CHEMBL54224)
Affinity DataIC50: 223nMAssay Description:Inhibition of HIV-1 reverse transcriptase E138K mutant-mediated polymerization reaction after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Rutgers University

Curated by ChEMBL
LigandPNGBDBM50369390(CHEMBL54224)
Affinity DataIC50: 223nMAssay Description:Inhibition of wild type HIV-1 reverse transcriptase-mediated polymerization reaction after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Rutgers University

Curated by ChEMBL
LigandPNGBDBM50369390(CHEMBL54224)
Affinity DataIC50: 244nMAssay Description:Inhibition of HIV-1 reverse transcriptase K101E mutant-mediated polymerization reaction after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed