BDBM50368971 CHEMBL4159987

SMILES [H][C@@]12CC[C@@](O)(C#CC(C)(C)C)[C@@]1(C)C[C@H](c1ccc(cc1)N(C)C)[C@]1([H])[C@@]3([H])CCC(=O)C=C3CC[C@@]21[H]

InChI Key InChIKey=OPYGWFILWDWQSX-UHFFFAOYSA-N

Data  4 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50368971   

TargetAndrogen receptor(Human)
Oric Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50368971(CHEMBL4159987)
Affinity DataEC50:  224nMAssay Description:Agonist activity at AR (unknown origin) expressed in human LNCaP cells incubated for 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Oric Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50368971(CHEMBL4159987)
Affinity DataIC50: 5.60nMAssay Description:Antagonist activity at human GR expressed in CHO-K1 cells assessed as reduction in dexamethasone-induced response incubated for 20 hrs by luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Oric Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50368971(CHEMBL4159987)
Affinity DataEC50: >2.50E+3nMAssay Description:Agonist activity at human GR expressed in CHO-K1 cells incubated for 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Oric Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50368971(CHEMBL4159987)
Affinity DataIC50: 165nMAssay Description:Antagonist activity at human androgen receptor in human LNCAP cells harboring firefly luciferase gene after 20 hrs by One-Glo luciferase reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Oric Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50368971(CHEMBL4159987)
Affinity DataIC50: 3.40nMAssay Description:Antagonist activity at human progesterone receptor expressed in CHO-K1 cells harboring firefly luciferase gene after 20 hrs by One-Glo luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Oric Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50368971(CHEMBL4159987)
Affinity DataEC50:  224nMAssay Description:Agonist activity at human androgen receptor in human LNCAP cells harboring firefly luciferase gene after 20 hrs by One-Glo luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Oric Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50368971(CHEMBL4159987)
Affinity DataIC50: 5.60nMAssay Description:Antagonist activity at human glucocorticoid receptor expressed in CHO-K1 cells harboring firefly luciferase gene after 20 hrs by One-Glo luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed