BDBM50368795 CHEMBL1791129

SMILES CC[C@@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H](CC(C)C)C(O)CC(=O)N(C)CC(C)C

InChI Key InChIKey=PXEPJAOGMFSTFB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50368795   

TargetEndothelin-converting enzyme 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50368795(CHEMBL1791129)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50368795(CHEMBL1791129)
Affinity DataIC50: 58nMAssay Description:Inhibition of conversion of hemoglobin by commercially purchased bovine spleen cathepsin D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50368795(CHEMBL1791129)
Affinity DataIC50: 1.00E+4nMpH: 6.0Assay Description:In vitro inhibition of partially purified human renin at pH 6.0.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed