BDBM50368627 CHEMBL4160653

SMILES COc1ccc2n(C)cc(\C=C3/SC(=O)NC3=O)c2c1

InChI Key InChIKey=JMLUECUVEMXFOZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50368627   

TargetGlycogen synthase kinase-3 beta(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50368627(CHEMBL4160653)
Affinity DataIC50: 890nMAssay Description:Inhibition of GSK3beta (unknown origin) using GS-2 peptide substrate incubated for 30 mins by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50368627(CHEMBL4160653)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of GSK3beta (unknown origin) pre-incubated for 30 mins followed by ULight-GS (Ser641/pSer657) peptide substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50368627(CHEMBL4160653)
Affinity DataIC50: 890nMAssay Description:Inhibition of recombinant human His6-taged GSK-3beta assessed as substrate phosphorylation incubated for 30 mins using RRRPASVPPSPSLSRHSSHQRR peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed