BDBM50366532 CHEMBL518966

SMILES CC(C)(C)c1ccc(C[C@]2(O)CC[C@H]3[C@@H]4CCc5cc(O)ccc5[C@H]4CC[C@]23C)cc1

InChI Key InChIKey=IOHXXLQQJOJOLB-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50366532   

TargetSteryl-sulfatase(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50366532(CHEMBL518966)
Affinity DataIC50: 12nMAssay Description:Inhibition of estrone sulfatase (unknown origin) transfected in HEK293 cells using [3H]E1S as substrate incubated for 2 hrs by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2017
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50366532(CHEMBL518966)
Affinity DataIC50: 28nMAssay Description:Estrone-sulfatase activity against homogenized human JEG-3 cells was determined by measuring the [3H]E1 obtained from [3H]E1SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50366532(CHEMBL518966)
Affinity DataIC50: 8.30nMAssay Description:Compound was tested for its ability to inhibit human embryonal kidney cell derived steroid sulfatase activity in transforming [3H]E1S (estrone sulfat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50366532(CHEMBL518966)
Affinity DataIC50: 14nMAssay Description:Compound was tested for its ability to inhibit the transformation of [C14]-DHEAS to DHEA by steroid sulfatase derived from human embryonal kidney cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50366532(CHEMBL518966)
Affinity DataIC50: 28nMAssay Description:Inhibition of steroid sulfatase activity of JEG-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50366532(CHEMBL518966)
Affinity DataIC50: 12nMAssay Description:Steroid sulfatase activity was determined in human embryonic kidney (HEK)-293 cells transfected with a sulfatase expression vector (pCMV-sulfa) using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50366532(CHEMBL518966)
Affinity DataIC50: 13nMAssay Description:Steroid sulfatase activity was determined in human embryonic kidney (HEK)-293 cells transfected with a sulfatase expression vector (pCMV-sulfa) using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50366532(CHEMBL518966)
Affinity DataIC50: 28nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50366532(CHEMBL518966)
Affinity DataIC50: 45nMAssay Description:Inhibition of steroid sulfatase (unknown origin) expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50366532(CHEMBL518966)
Affinity DataIC50: 28nMAssay Description:Reversible inhibition of steroid sulfatase in human JEG3 cells using [3H] E1S as substrate by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed