BDBM50365632 CHEMBL1957971
SMILES Cc1ccc2nc(c(NC3CCCCC3)n2c1)-c1ccc(cc1)N1CCOCC1
InChI Key InChIKey=ITCJJNJMYCQGTM-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50365632
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of 5-lipoxygenase in human polymorphonuclear leukocytes assessed as reduction in A23187 and AA-stimulated 5-LO product formation preincuba...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of 5-lipoxygenase in S100 cell free fraction of human polymorphonuclear leukocytes assessed as reduction in 5-LO product formation preincu...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-o...More data for this Ligand-Target Pair