BDBM50365476 CHEMBL1957361

SMILES CCOc1ccccc1-c1ccc(cc1)-c1nc2ccncc2c(O)c1C#N

InChI Key InChIKey=IMYDUDGJIZQSHN-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50365476   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50365476(CHEMBL1957361)Copy SMILESCopy InChI

Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50365476(CHEMBL1957361)Copy SMILESCopy InChI

Affinity DataIC50: 12nMAssay Description:Inhibition of human PDE10A catalytic domain expressed in Escherichia coli BL21-Gold(DE3) by enzyme inhibition assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL