BDBM50365175 CHEMBL1950196

SMILES CN1CCC2(CC1)C(=O)Nc1ccc(cc21)-c1ncc2ncn(Cc3ccc4ncccc4c3)c2n1

InChI Key InChIKey=GBVNFEAMYLVBID-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50365175   

TargetHepatocyte growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50365175(CHEMBL1950196)
Affinity DataIC50: 1.10E+6nMAssay Description:Inhibition of c-Met phosphorylation in human MKN45 cells after 1 hr by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50365175(CHEMBL1950196)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of 6-His-tagged human recombinant c-met using 5FAM-KKKSPGEYVNIGFG-NH2 as substrate after overnight incubation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed