BDBM50364235 CHEMBL1952280

SMILES CN(Cc1ccccc1)C(=O)N1CC(C1)O[C@@H](c1ccc(Cl)cc1)c1cccnc1Cl

InChI Key InChIKey=UQMBLWHHTBIECZ-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50364235   

TargetFatty-acid amide hydrolase 1(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50364235(CHEMBL1952280)
Affinity DataIC50: 887nMAssay Description:Inhibition of human FAAH expressed in CHO cells using 7-amino-4-methylcoumarine amide as substrate preincubated for 1 hr by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50364235(CHEMBL1952280)
Affinity DataIC50: 94nMAssay Description:Inhibition of rat FAAH using 7-amino-4-methylcoumarine amide as substrate preincubated for 1 hr by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50364235(CHEMBL1952280)
Affinity DataKi:  249nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50364235(CHEMBL1952280)
Affinity DataKi:  4.02E+3nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed