BDBM50363989 CHEMBL1949909

SMILES CS(=O)(=O)N1CCN(Cc2cc3nc(nc(N4CCOCC4)c3o2)-c2cccc3[nH]ncc23)CC1

InChI Key InChIKey=BHHHVZLVHGUWMT-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50363989   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Genentech

Curated by ChEMBL

LigandBDBM50363989(CHEMBL1949909)Copy SMILESCopy InChI

Affinity DataIC50: 3nMAssay Description:Inhibition of PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Genentech

Curated by ChEMBL

LigandBDBM50363989(CHEMBL1949909)Copy SMILESCopy InChI

Affinity DataIC50: 194nMAssay Description:Inhibition of PI3Kbeta using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL