BDBM50363988 CHEMBL1949908

SMILES CS(=O)(=O)N1CCN(Cc2cc3c(nc(nc3s2)-c2cccc3[nH]ncc23)N2CCOCC2)CC1

InChI Key InChIKey=GVKWJWXRSWROJM-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50363988   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Genentech

Curated by ChEMBL

LigandBDBM50363988(CHEMBL1949908)Copy SMILESCopy InChI

Affinity DataIC50: 3nMAssay Description:Inhibition of PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Genentech

Curated by ChEMBL

LigandBDBM50363988(CHEMBL1949908)Copy SMILESCopy InChI

Affinity DataIC50: 332nMAssay Description:Inhibition of PI3Kbeta using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL