BDBM50363957 CHEMBL1952210

SMILES COc1ccc(cc1)N1Cc2cnc(Nc3ccccc3)nc2N([C@@H]2CC[C@@H](O)C2)C1=O

InChI Key InChIKey=NDEFXZOKPREYOV-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50363957   

TargetEpidermal growth factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50363957(CHEMBL1952210)
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant His-tagged intracellular domain of EGFR using biotin-EEEEYFELV as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50363957(CHEMBL1952210)
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant EE-tagged intracellular domain of KDR using biotin-EEEEYFELVAKKKK as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C alpha type(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50363957(CHEMBL1952210)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of PKCalpha by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50363957(CHEMBL1952210)
Affinity DataIC50: 322nMAssay Description:Inhibition of Fyn by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 3(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50363957(CHEMBL1952210)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of EphB3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50363957(CHEMBL1952210)
Affinity DataIC50: 3.04E+3nMAssay Description:Inhibition of ERK2 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50363957(CHEMBL1952210)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of SGKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C delta type(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50363957(CHEMBL1952210)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of PKCdelta by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50363957(CHEMBL1952210)
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant EE-tagged intracellular domain of KDR using biotin-EEEEYFELVAKKKK as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50363957(CHEMBL1952210)
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant His-tagged intracellular domain of EGFR using biotin-EEEEYFELV as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50363957(CHEMBL1952210)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of CDK1/cyclin B by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed