BDBM50363893 CHEMBL1946124

SMILES Fc1ccc2C(=O)C(CCN3CCCN(CC3)c3ccc(Cl)cc3)Cc2c1

InChI Key InChIKey=TUSPVTWVRDALHT-UHFFFAOYSA-N

Data  24 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50363893   

TargetSodium-dependent serotonin transporter(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]-citalopram from human SERT by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]-citalopram from human SERT by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D4 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D4 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Rat)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]-N-methylspiperone from rat dopamine D4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]-Pentazocine from sigma 1 receptor (unknown origin) expressed in HEK293T cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]-Pentazocine from sigma 1 receptor (unknown origin) expressed in HEK293T cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  71nMAssay Description:Displacement of [3H]-LSD from human 5HT7 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]-LSD from human 5HT7 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  191nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  192nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  412nMAssay Description:Binding affinity at 5-HT2A receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  415nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  415nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  417nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  589nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  590nMAssay Description:Displacement of [3H]-N-methylspiperone from dopamine D3 receptor expressed in human MES-23.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  590nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  1.02E+3nMAssay Description:Displacement of [3H]-N-methylspiperone from dopamine D2 receptor expressed in human MES-23.5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  1.02E+3nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D2 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  1.02E+3nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D2 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  3.78E+3nMAssay Description:Displacement of [3H]-mesulergine from human 5HT2C receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  3.78E+3nMAssay Description:Binding affinity at 5-HT2C receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50363893(CHEMBL1946124)
Affinity DataKi:  3.80E+3nMAssay Description:Displacement of [3H]-mesulergine from human 5HT2C receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed