BDBM50363805 CHEMBL1946916

SMILES Oc1ccc2c3c4ccccc4[nH]c3c(=O)oc2c1

InChI Key InChIKey=PQILTUGKKMWZPN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50363805   

LigandPNGBDBM50363805(CHEMBL1946916)
Affinity DataIC50: 500nMAssay Description:Inhibition of GST-tagged rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate and [gamma-33P]ATP after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50363805(CHEMBL1946916)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human recombinant CDK5/p25 using [gamma-33P]ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50363805(CHEMBL1946916)
Affinity DataIC50: 74nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50363805(CHEMBL1946916)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of CDK5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50363805(CHEMBL1946916)
Affinity DataIC50: 380nMAssay Description:Inhibition of GSK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed