BDBM50363804 CHEMBL1946917
SMILES Oc1ccc2[nH]c3c(c2c1)c1ccc(O)cc1oc3=O
InChI Key InChIKey=AJTBUWMKUOLMNM-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50363804
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
Orleans University
Curated by ChEMBL
Orleans University
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of GST-tagged rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate and [gamma-33P]ATP after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human recombinant CDK5/p25 using [gamma-33P]ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 720nMAssay Description:Inhibition of CDK5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of GSK3 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of DNA topoisomerase 1 (unknown origin) at 50 uM measured by agar gel electrophoresisMore data for this Ligand-Target Pair