BDBM50363782 CHEMBL1945264::US9365508, A6 (3-Br)

SMILES CN(C)CCCCC(=O)Nc1ccc(NC(=S)NC(=O)c2cccc(Br)c2)cc1

InChI Key InChIKey=UZNNTHWEMCFBAY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50363782   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University Court of The University of St Andrews

US Patent
LigandPNGBDBM50363782(CHEMBL1945264 | US9365508, A6 (3-Br))
Affinity DataIC50: 3.99E+4nMAssay Description:All compounds were tested for inhibition of SIRT1 and SIRT2 using human recombinant enzymes available in the Fluor de Lys fluorescence-based assay ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University Court of The University of St Andrews

US Patent
LigandPNGBDBM50363782(CHEMBL1945264 | US9365508, A6 (3-Br))
Affinity DataIC50: 2.12E+4nMAssay Description:All compounds were tested for inhibition of SIRT1 and SIRT2 using human recombinant enzymes available in the Fluor de Lys fluorescence-based assay ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University Court of The University of St Andrews

US Patent
LigandPNGBDBM50363782(CHEMBL1945264 | US9365508, A6 (3-Br))
Affinity DataIC50: 3.99E+4nMAssay Description:Inhibition of recombinant human SitT1 by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University Court of The University of St Andrews

US Patent
LigandPNGBDBM50363782(CHEMBL1945264 | US9365508, A6 (3-Br))
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of recombinant human SitT2 by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed