BDBM50362903 CHEMBL1945953

SMILES O=c1[nH]c2ncc(nc2n1CC1CCOCC1)-c1ccc(cc1)-c1nnc[nH]1

InChI Key InChIKey=NHRWVYXOCMJUIS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50362903   

TargetSerine/threonine-protein kinase mTOR(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50362903(CHEMBL1945953)
Affinity DataIC50: 2nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50362903(CHEMBL1945953)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50362903(CHEMBL1945953)
Affinity DataIC50: 273nMAssay Description:Inhibition of mTOR-mediated S6 phosphorylation in human PC3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50362903(CHEMBL1945953)
Affinity DataIC50: 150nMAssay Description:Inhibition of mTOR-mediated Akt phosphorylation in human PC3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed