BDBM50362406 CHEMBL1940140

SMILES CCc1nccn1-c1nc(nc(n1)-c1cccc2[nH]ccc12)N1CCOCC1

InChI Key InChIKey=KSXKHJWAISWHSH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50362406   

TargetSerine/threonine-protein kinase mTOR(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50362406(CHEMBL1940140)
Affinity DataIC50: 26nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50362406(CHEMBL1940140)
Affinity DataIC50: 89nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50362406(CHEMBL1940140)
Affinity DataIC50: 96nMAssay Description:Inhibition of mTOR-mediated p70S6K phosphorylation at Thr389 in human PC3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed