BDBM50362169 CHEMBL1938680

SMILES Clc1ccc(cc1)-c1ccc(o1)C(=O)Nc1ccc(cc1)N1CCNCC1

InChI Key InChIKey=CAIGVNVLJGDZSF-UHFFFAOYSA-N

Data  16 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50362169   

TargetRho-associated protein kinase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50362169(CHEMBL1938680)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ROCK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50362169(CHEMBL1938680)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CAMK4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50362169(CHEMBL1938680)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human IRAK4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50362169(CHEMBL1938680)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human AKT1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50362169(CHEMBL1938680)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MK2 using Acam peptide as substrate incubated for 30 mins prior to substrate addition measured after 10 mins using 2 uM ATP by DELFIA a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCasein kinase I isoform delta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50362169(CHEMBL1938680)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CSNK1DMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50362169(CHEMBL1938680)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human LCKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50362169(CHEMBL1938680)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human IKKBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50362169(CHEMBL1938680)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50362169(CHEMBL1938680)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of MK2 using Acam peptide as substrate incubated for 30 mins prior to substrate addition measured after 10 mins using 100 uM ATP by DELFIA...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50362169(CHEMBL1938680)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human TSSK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50362169(CHEMBL1938680)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human MST2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50362169(CHEMBL1938680)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human METMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50362169(CHEMBL1938680)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MK2 (unknown origin) phosphorylation using TAMRA labeled peptide as substrate incubated 30 mins before substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50362169(CHEMBL1938680)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of MK2-mediated HSP27 phosphorylation at Ser78 in LPS-stimulated human THP-1 cells pre-incubated for 60 mins before LPS treatment measured...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50362169(CHEMBL1938680)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of MK2 using TAMRA-labeled peptide as substrate pre-incubated for 30 mins prior substrate addition measured after 30 mins incubation in da...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50362169(CHEMBL1938680)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CHK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50362169(CHEMBL1938680)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of MK2-mediated HSP27 phosphorylation in IL-1beta stimulated human SW1353 cells incubated for 30 mins prior to IL-1beta-stimulation measur...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed