BDBM50362149 CHEMBL1940668

SMILES [O-][N+](=O)c1cc(ccc1NCCSc1ccccc1)S(=O)(=O)NC(=O)c1ccc(NC(=O)c2ccccc2)cc1

InChI Key InChIKey=TVPSJQIEGFPHDV-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50362149   

TargetBcl-2-like protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50362149(CHEMBL1940668)
Affinity DataKi:  630nMAssay Description:Inhibition of 5-FAM-Bid peptide binding to Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362149(CHEMBL1940668)
Affinity DataKi:  1.67E+3nMAssay Description:Binding affinity to Bcl-2 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362149(CHEMBL1940668)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of 5-FAM-Bid peptide binding to Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50362149(CHEMBL1940668)
Affinity DataKi:  2.51E+3nMAssay Description:Binding affinity to Bcl-xL by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362149(CHEMBL1940668)
Affinity DataKi:  4.16E+3nMAssay Description:Binding affinity to Mcl-1 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362149(CHEMBL1940668)
Affinity DataKi:  6.70E+3nMAssay Description:Inhibition of 5-FAM-Bid peptide binding to MCL-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed