BDBM50361601 CHEMBL1939846

SMILES CC(C)[C@H]1N(CC(=O)N(O)C1=O)S(=O)(=O)c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=RQCBSNJRFVZHOS-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50361601   

TargetMatrix metalloproteinase-14(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361601(CHEMBL1939846)
Affinity DataIC50: 83nMAssay Description:Inhibition of human recombinant MMP14 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361601(CHEMBL1939846)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant MMP9 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361601(CHEMBL1939846)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of MMP1 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361601(CHEMBL1939846)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant MMP2 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361601(CHEMBL1939846)
Affinity DataIC50: 220nMAssay Description:Inhibition of MMP3 using Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361601(CHEMBL1939846)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant MMP8 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361601(CHEMBL1939846)
Affinity DataIC50: 23nMAssay Description:Inhibition of MMP12 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361601(CHEMBL1939846)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of MMP13 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361601(CHEMBL1939846)
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant MMP16 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361601(CHEMBL1939846)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TACE using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed