BDBM50361576 CHEMBL1939497::CHEMBL1939498
SMILES CN1CCCC[C@H]1[C@@H](NC(=O)c1cccc(c1I)C(F)(F)F)c1ccccc1
InChI Key InChIKey=NVMKECIXYGQWGJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50361576
Affinity DataKd: 1.60nMAssay Description:Binding affinity to GlyT1 in rat cortical brain homogenate after 60 mins by gamma countingMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of GlyT1 in human JAR cells assessed as inhibition of [3H]glycine uptake preincubated for 1 mins measured after 2 hrs by liquid scintillat...More data for this Ligand-Target Pair