BDBM50360998 CHEMBL1935435

SMILES Fc1ccc(Cn2c(nc3ccccc23)C2CCCN(Cc3ncco3)C2)cc1

InChI Key InChIKey=LUFOXAFMTZDQHJ-UHFFFAOYSA-N

Data  5 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50360998   

TargetCytochrome P450 2D6(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50360998(CHEMBL1935435)
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50360998(CHEMBL1935435)
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50360998(CHEMBL1935435)
Affinity DataKi:  8.10nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50360998(CHEMBL1935435)
Affinity DataKi:  8.10nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50360998(CHEMBL1935435)
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of [3H]dofetolide from human ErgMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50360998(CHEMBL1935435)
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of [3H]dofetolide from human ErgMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50360998(CHEMBL1935435)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of muscarinic M1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed