BDBM50359897 CHEMBL264164

SMILES Clc1ccccc1\C=C1/S\C(NC1=O)=N/c1nsc2ccccc12

InChI Key InChIKey=WFCYAEPJWPWCIM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50359897   

TargetStromelysin-1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50359897(CHEMBL264164)
Affinity DataIC50: 6.19E+3nMAssay Description:Inhibition of MMP3 catalytic domain (unknown origin) assessed as reduction in hydrolysis of Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50359897(CHEMBL264164)
Affinity DataIC50: 8.94E+4nMAssay Description:Inhibition of MMP13 catalytic domain (unknown origin) assessed as reduction in hydrolysis of Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate measured f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50359897(CHEMBL264164)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50359897(CHEMBL264164)
Affinity DataIC50: 4.36E+4nMAssay Description:Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed