BDBM50359006 CHEMBL1738936

SMILES Cc1ccc(OCCn2c(SCCOc3ccccc3)nc3ccccc23)cc1

InChI Key InChIKey=PNCBJXVNIRRHJP-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50359006   

TargetAndrogen receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandPNGBDBM50359006(CHEMBL1738936)
Affinity DataIC50: 1.31E+4nMAssay Description:Transcriptional activity at human androgen receptor BF3 site stably transfected in eGFP-expressing human LNCAP cells after 5 days by fluorometric ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandPNGBDBM50359006(CHEMBL1738936)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DHT from human androgen receptor expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandPNGBDBM50359006(CHEMBL1738936)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of 5-iodoacetamidofluorescein labeled SRC23 peptide CKENALLRYLLDKDD human androgen receptor AF2 site expressed in Escherichia coli BL21 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandPNGBDBM50359006(CHEMBL1738936)
Affinity DataIC50: 1.31E+4nMAssay Description:Inhibition of BF3 site of androgen receptor in human LNCAP cells expressing ARR2PB after 3 days by eGFP transcriptional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)