BDBM50358913 CHEMBL1923589

SMILES COc1ccc(cn1)-c1ccc2cnc(Nc3ccc(N4CCN(C)CC4)c(F)c3)nn12

InChI Key InChIKey=BMRWKIYVKWSZAZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358913   

TargetTyrosine-protein kinase JAK2(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50358913(CHEMBL1923589)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant JAK2 using biotinyl-amino-hexanoyl-EQEDEPEGDYFEWLE-amide as substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed