BDBM50358762 CHEMBL1922475

SMILES Clc1cc2C(=O)NC(=O)c2cc1Nc1cccc(NC(=O)c2cccc(I)c2)c1

InChI Key InChIKey=NQTHPBZIGQQCGW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358762   

TargetSerine/threonine-protein kinase B-raf(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50358762(CHEMBL1922475)
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant his6-tagged B-Raf expressed in Sf9 cells assessed as inhibition of MEK1 phosphorylation after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed