BDBM50358760 CHEMBL1922473

SMILES Clc1cccc(c1)C(=O)Nc1cccc(Nc2cc3C(=O)NC(=O)c3cc2Cl)c1

InChI Key InChIKey=KABJVMJWLHOYFO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358760   

TargetSerine/threonine-protein kinase B-raf(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50358760(CHEMBL1922473)
Affinity DataIC50: 117nMAssay Description:Inhibition of human recombinant his6-tagged B-Raf expressed in Sf9 cells assessed as inhibition of MEK1 phosphorylation after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed