BDBM50358353 CHEMBL1922702

SMILES Cn1c2ccc(cc2n(Cc2ccc(cc2)C(=O)Nc2nnn[nH]2)c1=Nc1ccc(OC(F)(F)F)cc1)C(F)(F)F

InChI Key InChIKey=FVYMLQKMUWTKBV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50358353   

TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50358353(CHEMBL1922702)
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 4 to 12 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50358353(CHEMBL1922702)
Affinity DataIC50: 49nMAssay Description:Antagonist activity at human GCGR expressed in CHO cells assessed as inhibition of glucagon-induced [125I]cAMP accumulation after 30 mins by scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed