BDBM50357614 CHEMBL1915648

SMILES CC(C)CNC(=O)c1cccc2c3cnccc3c(Nc3ccccc3Cl)nc12

InChI Key InChIKey=XLHVTKIMNYRMGW-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50357614   

TargetSerine/threonine-protein kinase pim-1(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357614(CHEMBL1915648)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 30 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357614(CHEMBL1915648)
Affinity DataEC50:  980nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357614(CHEMBL1915648)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 5 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed