BDBM50357612 CHEMBL1915646

SMILES CCNC(=O)c1cccc2c1nc(Nc1ccccc1Cl)c1ccncc21

InChI Key InChIKey=FOPGQICEKPAAOV-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50357612   

TargetSerine/threonine-protein kinase pim-1(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357612(CHEMBL1915646)
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 30 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357612(CHEMBL1915646)
Affinity DataEC50:  210nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357612(CHEMBL1915646)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 5 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed