BDBM50357287 CHEMBL1916686

SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CN1[C@@H](C)[C@H](OC1=O)c1ccccc1)C(F)(F)F

InChI Key InChIKey=ICMOGANJAUQPKT-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50357287   

TargetProstaglandin D2 receptor 2(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357287(CHEMBL1916686)
Affinity DataIC50: 4.50E+3nMAssay Description:Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357287(CHEMBL1916686)
Affinity DataIC50: 180nMAssay Description:Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357287(CHEMBL1916686)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357287(CHEMBL1916686)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357287(CHEMBL1916686)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357287(CHEMBL1916686)
Affinity DataIC50: 3.13E+4nMAssay Description:Displacement of [3H]-PGD2 from human DP1 receptor expressed in human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357287(CHEMBL1916686)
Affinity DataIC50: 6.37E+4nMAssay Description:Displacement of [3H]-SQ-29,548 from human TP receptor expressed in human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed