BDBM50357286 CHEMBL1916700

SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccccc1

InChI Key InChIKey=CUWBXEPNHLJYKS-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50357286   

TargetProstaglandin D2 receptor 2(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357286(CHEMBL1916700)
Affinity DataIC50: 5nMAssay Description:Inhibition of human prostanoid DP2 receptor in human whole bood assessed as eosinophil shape change preincubated for 15 mins before addition of PGD2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357286(CHEMBL1916700)
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357286(CHEMBL1916700)
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357286(CHEMBL1916700)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357286(CHEMBL1916700)
Affinity DataIC50: 5.62E+4nMAssay Description:Displacement of [3H]-iloprost from human prostanoid IP receptor expressed in human 293T cells membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357286(CHEMBL1916700)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357286(CHEMBL1916700)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357286(CHEMBL1916700)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357286(CHEMBL1916700)
Affinity DataIC50: 4.00E+3nMAssay Description:Displacement of [3H]-PGD2 from human DP1 receptor expressed in human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357286(CHEMBL1916700)
Affinity DataIC50: 2.30E+4nMAssay Description:Displacement of [3H]-SQ-29,548 from human TP receptor expressed in human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed