BDBM50357221 CHEMBL442218::US20230322715, Compound ALK-10

SMILES OC(=O)[C@@H]1CSC(=O)N1

InChI Key InChIKey=BMLMGCPTLHPWPY-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50357221   

TargetRNA demethylase ALKBH5(Human)
University of California

US Patent
LigandPNGBDBM50357221(CHEMBL442218 | US20230322715, Compound ALK-10)
Affinity DataIC50: 1.70E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University of California

US Patent
LigandPNGBDBM50357221(CHEMBL442218 | US20230322715, Compound ALK-10)
Affinity DataIC50: 4.00E+4nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetProton-coupled amino acid transporter 1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50357221(CHEMBL442218 | US20230322715, Compound ALK-10)
Affinity DataKi:  4.60E+7nMAssay Description:Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed