BDBM50355867 CHEMBL1909735

SMILES Fc1ccc(cc1)-c1c[nH]nn1

InChI Key InChIKey=KYQRWVUQWNZHFU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50355867   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50355867(CHEMBL1909735)
Affinity DataIC50: 5.80E+5nMAssay Description:Inhibition of human recombinant indoleamine-2,3-dioxygenase expressed in Escherichia coli BL21 using L-tryptophan as substrate after 30 mins by micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
Ludwig Center For Cancer Research of The University of Lausanne

Curated by ChEMBL
LigandPNGBDBM50355867(CHEMBL1909735)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse TDO in P815 clone 12 cells by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50355867(CHEMBL1909735)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human IDO1 transfected in mouse P815B clone-6 cells by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
Ludwig Center For Cancer Research of The University of Lausanne

Curated by ChEMBL
LigandPNGBDBM50355867(CHEMBL1909735)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Ludwig Center For Cancer Research of The University of Lausanne

Curated by ChEMBL
LigandPNGBDBM50355867(CHEMBL1909735)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human TDO transfected in mouse P815B clone 19 cells by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50355867(CHEMBL1909735)
Affinity DataIC50: 1.90E+5nMpH: 6.5Assay Description:Inhibition of human recombinant N-terminal His-tagged IDO1 (Ala2 to Gly403) overexpressed in Escherichia coli BL21 at pH 6.5 after 60 mins by HPLC an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed