BDBM50355665 CHEMBL1910971

SMILES NC(CCl)=NCCC[C@H](NC(=O)c1ccccc1C(O)=O)C(N)=O

InChI Key InChIKey=VUCFCRGOVAAFJN-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50355665   

TargetProtein-arginine deiminase type-1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50355665(CHEMBL1910971)
Affinity DataIC50: 840nMAssay Description:Irreversible inhibition of PAD1 assessed as hydrolysis of benzoyl-L-arginine ethyl ester preincubated for 15 mins measured after 15 mins by fluoromet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetProtein-arginine deiminase type-2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50355665(CHEMBL1910971)
Affinity DataIC50: 6.20E+3nMAssay Description:Irreversible inhibition of PAD2 assessed as hydrolysis of benzoyl-L-arginine ethyl ester preincubated for 15 mins measured after 15 mins by fluoromet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetProtein-arginine deiminase type-4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50355665(CHEMBL1910971)
Affinity DataIC50: 2.20E+3nMAssay Description:Irreversible inhibition of PAD4 assessed as hydrolysis of benzoyl-L-arginine ethyl ester preincubated for 15 mins measured after 15 mins by fluoromet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetProtein-arginine deiminase type-3(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50355665(CHEMBL1910971)
Affinity DataIC50: 690nMAssay Description:Irreversible inhibition of PAD3 assessed as hydrolysis of benzoyl-L-arginine ethyl ester preincubated for 15 mins measured after 15 mins by fluoromet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetProtein-arginine deiminase type-4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50355665(CHEMBL1910971)
Affinity DataKi:  1.30E+4nMAssay Description:Irreversible inhibition of PAD4 assessed as hydrolysis of benzoyl-L-arginine ethyl ester preincubated for 15 mins measured after 15 mins by fluoromet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetProtein-arginine deiminase type-3(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50355665(CHEMBL1910971)
Affinity DataKi:  2.90E+4nMAssay Description:Irreversible inhibition of PAD3 assessed as hydrolysis of benzoyl-L-arginine ethyl ester preincubated for 15 mins measured after 15 mins by fluoromet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed