BDBM50355479 CHEMBL1835746

SMILES COc1ccccc1Nc1nc(N)n(n1)-c1cc(NCCN(C)C)ncn1

InChI Key InChIKey=XCHZMPYWMULFBJ-UHFFFAOYSA-N

Data  5 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50355479   

TargetMast/stem cell growth factor receptor Kit(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355479(CHEMBL1835746)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of human recombinant c-Kit by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355479(CHEMBL1835746)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant FLT3 by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355479(CHEMBL1835746)
Affinity DataKi:  1nMAssay Description:Displacement of [33P]ATP from human recombinant FLT3 domain after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50355479(CHEMBL1835746)
Affinity DataKi:  78nMAssay Description:Inhibition of IRAK4 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355479(CHEMBL1835746)
Affinity DataKi:  270nMAssay Description:Displacement of [33P]ATP from human recombinant c-KIT domain after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50355479(CHEMBL1835746)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of Aurora A by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50355479(CHEMBL1835746)
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of JAK2 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed