BDBM50354565 CHEMBL1836719

SMILES CSc1ccc(cc1)-c1cc2ncnc(SCC(O)=O)c2s1

InChI Key InChIKey=KJCQGDBVLKOAHP-UHFFFAOYSA-N

Data  3 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50354565   

LigandPNGBDBM50354565(CHEMBL1836719)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of TPL2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 17A(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50354565(CHEMBL1836719)
Affinity DataKd:  230nMAssay Description:Binding affinity to STK17A (unknown origin) by KINOMEscan scanMAX assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 17B(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50354565(CHEMBL1836719)
Affinity DataKd:  3.80nMAssay Description:Binding affinity to N-terminal His-tagged STK17B kinase domain (25 to 329 residues) (unknown origin) expressed in Escherichia coli by KINOMEscan scan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 17B(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50354565(CHEMBL1836719)
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal His-tagged STK17B kinase domain (25 to 329 residues) (unknown origin) expressed in Escherichia coli incubated for 90 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 17B(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50354565(CHEMBL1836719)
Affinity DataIC50: 210nMAssay Description:Binding affinity to C-terminal nano-luciferase tagged STK17B (unknown origin) expressed in HEK293 cells incubated for 2 hrs by nano-BRET assay based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed