BDBM50354493 CHEMBL409662

SMILES CCC1(CCCCN2CCN(CC2)c2ccc(Cl)cc2)C(=O)Nc2cc(F)ccc12

InChI Key InChIKey=QFHWIGIQQPTXBG-UHFFFAOYSA-N

Data  13 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50354493   

Target5-hydroxytryptamine receptor 7(Human)
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354493(CHEMBL409662)
Affinity DataKi:  0.790nMAssay Description:Displacement of [3H]CT from human 5-HT7 receptor expressed in CHO cells by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354493(CHEMBL409662)
Affinity DataKi:  0.790nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354493(CHEMBL409662)
Affinity DataKi:  0.790nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354493(CHEMBL409662)
Affinity DataKi:  19nMAssay Description:Binding affinity to 5-HT2A receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354493(CHEMBL409662)
Affinity DataKi:  19.4nMAssay Description:Inhibition of 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354493(CHEMBL409662)
Affinity DataKi:  71.3nMAssay Description:Inhibition of adrenergic alpha-1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354493(CHEMBL409662)
Affinity DataKi:  187nMAssay Description:Inhibition of 5HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354493(CHEMBL409662)
Affinity DataKi:  358nMAssay Description:Inhibition of 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354493(CHEMBL409662)
Affinity DataKi:  950nMAssay Description:Inhibition of dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354493(CHEMBL409662)
Affinity DataKi:  1.61E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-HT1A receptor in rat frontal cortex membrane after 45 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354493(CHEMBL409662)
Affinity DataKi:  1.61E+3nMAssay Description:Inhibition of 5HT1A receptor in rat frontal cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50354493(CHEMBL409662)
Affinity DataKi:  1.61E+3nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354493(CHEMBL409662)
Affinity DataKi:  3.36E+3nMAssay Description:Inhibition of dopamine D1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed